10 suppositories per box Ingredients: A proprietary blend of superoxide dismutase, catalase and melatonin in a base of organic cocoa butter. The above ingredients do not survive digestion well, therefore it is more effective as a suppository. Take one suppository every third day before going to bed. Aging is associated with increased levels of soft tissue calcium, scarring and free radical damage. As such, you may want to consider one medicardium, one notoplex and one rejuvelon suppository once a week once you reach the age of 45.